Psoriasis Biologics Face Off in Drug Survival Study  - Takeaways - MDSpire

Psoriasis Biologics Face Off in Drug Survival Study 

  • By

  • Julie Greenbaum

  • January 14, 2026

  • 2 min

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  • 1

    Ustekinumab showed higher drug survival than adalimumab or secukinumab in bionaive psoriasis patients.

  • 2

    In bioexperienced patients, bimekizumab, guselkumab, and risankizumab had the highest 2-year drug survival rates.

  • 3

    The study analyzed data from the DERMBIO registry, covering over 90% of biologic-treated psoriasis patients in Denmark.

  • 4

    At 5 years, the treatment discontinuation risk was lowest for ustekinumab at 37%, compared to 51% for adalimumab.

  • 5

    Bimekizumab had the highest unadjusted 1-year drug survival at 83% among bioexperienced patients.

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