Psoriasis Biologics Face Off in Drug Survival Study
Danish registry data reveal differences in treatment persistence
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By
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Julie Greenbaum
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January 14, 2026
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1
Ustekinumab showed higher drug survival than adalimumab or secukinumab in bionaive psoriasis patients.
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In bioexperienced patients, bimekizumab, guselkumab, and risankizumab had the highest 2-year drug survival rates.
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The study analyzed data from the DERMBIO registry, covering over 90% of biologic-treated psoriasis patients in Denmark.
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At 5 years, the treatment discontinuation risk was lowest for ustekinumab at 37%, compared to 51% for adalimumab.
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Bimekizumab had the highest unadjusted 1-year drug survival at 83% among bioexperienced patients.