A systematic review of explainable artificial intelligence methods for speech-based cognitive decline detection - Takeaways - MDSpire

A systematic review of explainable artificial intelligence methods for speech-based cognitive decline detection

  • By

  • Ravi Shankar

  • Ziyu Goh

  • Fiona Devi

  • Qian Xu

  • November 26, 2025

  • 0 min

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  • 1

    AI models analyzing speech can effectively detect cognitive decline, achieving performance comparable to traditional clinical assessments.

  • 2

    The 'black box' nature of many AI models hinders their clinical adoption, as healthcare professionals require transparent decision-making processes.

  • 3

    Explainable AI (XAI) techniques, such as SHAP and LIME, enhance the interpretability of AI models used for detecting cognitive decline through speech.

  • 4

    Speech changes, including reduced lexical diversity and altered speech fluency, serve as early indicators of cognitive decline, suitable for AI analysis.

  • 5

    Despite advancements, significant gaps remain in stakeholder engagement, real-world validation, and standardized evaluation frameworks for XAI in healthcare.

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