Cytokine and Humoral Immune Responses to a Goatpox Vaccine in Mithun (Bos frontalis): A Year-Long Field Investigation - Takeaways - MDSpire

Cytokine and Humoral Immune Responses to a Goatpox Vaccine in Mithun (Bos frontalis): A Year-Long Field Investigation

  • By

  • Gundallahalli Bayyappa Manjunatha Reddy

  • Vikram Ramesh

  • Yallappa M. Somagond

  • Plabita Goswami

  • Selvaraj Ragulraj

  • Hlawndo Lalzampuia

  • Suchismitha Pal

  • Sudeep Nagaraj

  • Sunil Tadakod

  • Uzma Jabeen

  • Shraddha Bijalwan

  • Muthannan Andavar Ramakrishnan

  • Baldev Raj Gulati

  • Patil Shivanagowda Girish

  • April 21, 2026

  • 0 min

Share

  • 1

    A year-long study assessed the immune response to a goatpox vaccine in seronegative Mithun, addressing Lumpy Skin Disease (LSD) concerns in Northeast India.

  • 2

    The goatpox vaccine was found safe, with no adverse reactions or viral shedding detected in Mithun during the 12-month observation period.

  • 3

    Significant seroconversion and cytokine upregulation occurred post-vaccination, peaking at 30 days, indicating a robust immune response.

  • 4

    Spatial mapping revealed ongoing LSDV activity in Mithun populations, highlighting the need for effective vaccination strategies.

  • 5

    This study provides essential baseline data for future evaluations of LSD control measures in Mithun, a vulnerable bovine species.

Original Source(s)

Cytokine and Humoral Immune Responses to a Goatpox Vaccine in Mithun (Bos frontalis): A Year-Long Field Investigation

  • by Gundallahalli Bayyappa Manjunatha Reddy, Vikram Ramesh, Yallappa M. Somagond, Plabita Goswami, Selvaraj Ragulraj, Hlawndo Lalzampuia, Suchismitha Pal, Sudeep Nagaraj, Sunil Tadakod, Uzma Jabeen, Shraddha Bijalwan, Muthannan Andavar Ramakrishnan, Baldev Raj Gulati, Patil Shivanagowda Girish

  • April 21, 2026

Related Content

Senate Report Details Early Myocarditis Signals After COVID-19 Vaccination

Investigative report cites internal communications, VAERS data, and CDC case reviews describing myocarditis and pericarditis reports in adolescents and young adults after mRNA COVID-19 vaccination.

Effectiveness of Nirmatrelvir/Ritonavir for Outpatients in the Era of Omicron, Vaccination, and Previous Infection: A Meta-analysis

Medical Oddities: Ancient Practice Calms Modern BP

Ancient workouts, anxious ears, tea gains, limb regrowth, and furry tongues collide.