Metabolic Risk Factors Are Associated With Weight Status Change Over Four Years in Children Aged 4–6 Years With Obesity - Takeaways - MDSpire
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Association of Metabolic Risk Factors with Changes in Weight Status Over Four Years Among Obese Children Aged 4 to 6 Years

  • By

  • Markus Brissman

  • Anna Ek

  • Stella Wennborg

  • Karin Nordin

  • Karin Eli

  • Annika Janson

  • Paulina Nowicka

  • June 5, 2026

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  • 1

    The study assessed long-term metabolic health in obese children aged 4-6 years using data from the More and Less trial.

  • 2

    Obesity in early childhood is linked to increased risks of type 2 diabetes, cardiovascular disease, and non-alcoholic fatty liver disease.

  • 3

    Only two obesity treatment programs for preschool-aged children have been evaluated in randomized controlled trials to date.

  • 4

    Metabolic markers analyzed included hsCRP, glucose, HbA1c, insulin, cholesterol levels, and liver enzymes.

  • 5

    Participants were categorized based on BMI SDS reduction, with cutoffs associated with improvements in metabolic health.

Original Source(s)

Metabolic Risk Factors Are Associated With Weight Status Change Over Four Years in Children Aged 4–6 Years With Obesity

  • by Markus Brissman, Anna Ek, Stella Wennborg, Karin Nordin, Karin Eli, Annika Janson, Paulina Nowicka

  • June 5, 2026

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