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AMD incidence may be higher in lupus

  • By

  • Andrea Surnit

  • October 27, 2026

  • 4 min

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  • 1

    In a South Korean claims-based cohort, 9,496 adults aged 45 years or older with incident SLE were matched with 28,488 controls and followed for a mean of 6.7 and 7 years, respectively.

  • 2

    Overall AMD incidence was 49.1 per 10,000 person-years among patients with SLE and 26.7 among controls.

  • 3

    Neovascular AMD incidence was 10.5 per 10,000 person-years in patients with SLE and 3.3 in controls; dry AMD incidence was 38.6 and 23.4, respectively.

  • 4

    Treatment-defined severe SLE was not associated with significantly higher incidence of overall, dry, or neovascular AMD than nonsevere SLE.

  • 5

    Although neovascular AMD likelihood versus controls was higher in both hydroxychloroquine exposure groups, longer exposure was not significantly associated with higher neovascular AMD hazards within t

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