Twenty-five-year trends in mortality and major morbidity among very low birth weight infants at a Saudi tertiary centre: improving morbidity despite expanding resuscitation at the limits of viability - Takeaways - MDSpire

Twenty-five-year trends in mortality and major morbidity among very low birth weight infants at a Saudi tertiary centre: improving morbidity despite expanding resuscitation at the limits of viability

  • By

  • Lana A. Shaiba

  • Adnan Hadid

  • Khalid Almoosa

  • Abdulmalik Alharbi

  • Khalid Alharbi

  • Mohammed Albabtain

  • Badr Sobaih

  • July 9, 2026

  • 0 min

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  • 1

    This study analyzed 25-year trends in survival and morbidity of very low birth weight infants at a Saudi tertiary center.

  • 2

    Crude survival rates for VLBW infants declined significantly from 88.7% to 79.0% across three study periods.

  • 3

    Among infants ≥24 weeks, survival rates remained relatively stable, indicating the decline was driven by infants admitted at 22–24 weeks.

  • 4

    Substantial reductions in early-onset sepsis, late-onset sepsis, necrotising enterocolitis, and severe retinopathy were observed.

  • 5

    The study highlights the need for standardized national benchmarking and multicenter surveillance in neonatal care.

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