Analysis of mortality risk and influencing factors in female patients with young-onset type 2 diabetes - Takeaways - MDSpire

Analysis of mortality risk and influencing factors in female patients with young-onset type 2 diabetes

  • By

  • Ling Xiang

  • Mingmin Zhu

  • Zi Yan

  • Zhijin Geng

  • Yuankai Zhou

  • Zhongming Sun

  • Dandan Miao

  • Yong Zhang

  • Jinyi Zhou

  • Enchun Pan

  • Wen Hu

  • April 17, 2026

  • 0 min

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  • 1

    The study analyzed 5,984 female patients with type 2 diabetes mellitus, focusing on early-onset cases and their mortality risk.

  • 2

    The overall all-cause mortality rate was 21.6%, with young-onset diabetes patients showing lower mortality compared to late-onset patients.

  • 3

    Postmenopausal women with young-onset diabetes had the highest mortality rate at 24%, while premenopausal women had the lowest at 3.7%.

  • 4

    The triglyceride–glucose–body mass index (TyG-BMI) was identified as a protective factor, reducing mortality risk by 2% per standard deviation increase.

  • 5

    Early identification and intervention of TyG-BMI levels in postmenopausal women with young-onset diabetes may help reduce mortality risk.

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