Conversion-oriented multimodal therapy enabling definitive surgery in a patient with FIGO stage IVA cervical cancer at high risk of fistula formation: a case report - Takeaways - MDSpire

Conversion-oriented multimodal therapy enabling definitive surgery in a patient with FIGO stage IVA cervical cancer at high risk of fistula formation: a case report

  • By

  • Yanling Yuan

  • Wanming He

  • Lihua Tong

  • Yu Yang

  • Wen Yang

  • June 17, 2026

  • 0 min

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  • 1

    A 59-year-old woman with FIGO stage IVA cervical cancer presented with severe anemia and renal dysfunction due to extensive tumor invasion.

  • 2

    Emergent hemostatic radiotherapy effectively controlled massive vaginal bleeding and stabilized the patient's clinical condition.

  • 3

    An individualized multimodal treatment strategy, including radiotherapy, targeted therapy, and immunotherapy, was implemented to facilitate radical surgery.

  • 4

    Image-guided radiotherapy monitoring allowed for adaptive replanning, reducing radiation exposure to adjacent organs while achieving tumor regression.

  • 5

    The patient underwent successful radical surgery with a pathological complete response and no recurrence during follow-up, highlighting the treatment's potential.

Original Source(s)

Conversion-oriented multimodal therapy enabling definitive surgery in a patient with FIGO stage IVA cervical cancer at high risk of fistula formation: a case report

  • by Yanling Yuan, Wanming He, Lihua Tong, Yu Yang, Wen Yang

  • June 17, 2026

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