Early osseointegration of two in-house 3D-printed porous titanium implant designs: an in vivo sheep study - Takeaways - MDSpire

Early osseointegration of two in-house 3D-printed porous titanium implant designs: an in vivo sheep study

  • By

  • Anna B. Borgognoni

  • Sarah S. Freund

  • Jørgen Baas

  • Michael M. Bendtsen

  • Jeppe S. Byskov

  • Bahram Ranjkesh

  • Jens R. Nyengaard

  • Ruben Pauwels

  • Thomas Baad-Hansen

  • May 25, 2026

  • 0 min

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  • 1

    This study evaluated early osseointegration of two custom 3D-printed titanium implants with different pore sizes and porosities in sheep.

  • 2

    No significant differences were found in mechanical strength, energy, or stiffness between the two implant designs after 4 weeks.

  • 3

    Histomorphometric analysis showed no significant differences in bone or fibrous tissue fractions between the two implant groups.

  • 4

    Both implant designs maintained sufficient structural integrity and did not elicit any foreign body reactions in the specimens.

  • 5

    Future research should explore the performance of these implants under weight-bearing conditions to assess long-term stability.

Original Source(s)

Early osseointegration of two in-house 3D-printed porous titanium implant designs: an in vivo sheep study

  • by Anna B. Borgognoni, Sarah S. Freund, Jørgen Baas, Michael M. Bendtsen, Jeppe S. Byskov, Bahram Ranjkesh, Jens R. Nyengaard, Ruben Pauwels, Thomas Baad-Hansen

  • May 25, 2026

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