Epidemiological trends in sepsis in Spain: incidence, in-hospital mortality, and healthcare burden (2017-2022) - Takeaways - MDSpire
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Trends in Sepsis Epidemiology in Spain: Analysis of Incidence, In-Hospital Mortality, and Healthcare Impact (2017-2022)

  • By

  • Rocío López Herrero

  • Paula Martínez-Jiménez

  • Daniel Ortiz del Olmo

  • Rosa Dolores Prieto-Utrera

  • Rosa Cobo-Zubia

  • Adrián García- Concejo

  • Mario Lorenzo-López

  • Irina Rebollo-Mato

  • Fernando Vaquerizo-Villar

  • Rodrigo Poves-Álvarez

  • Esther Gómez-Sánchez

  • Eduardo Tamayo

  • September 25, 2026

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  • 1

    Sepsis remains a major global health challenge, with recent estimates suggesting approximately 166 million cases and 21.4 million related deaths annually.

  • 2

    In Spain, a nationwide study from 2017 through 2022 examined sepsis incidence, in-hospital mortality, clinical characteristics, infection sources, and healthcare burden using the Minimum Basic Data Set.

  • 3

    Researchers retrospectively analyzed hospitalized patients with sepsis and compared the 2017-2022 findings with previously published Spanish data to assess changes over time.

  • 4

    A separate analysis excluding COVID-19-associated hospitalizations was conducted to distinguish underlying sepsis trends from those associated with COVID-19, although indirect pandemic effects could not be eliminated.

  • 5

    The Minimum Basic Data Set captures 99.5% of hospital discharges in Spain, providing broad national coverage, although the administrative data remain subject to coding-related limitations.

Original Source(s)

Epidemiological trends in sepsis in Spain: incidence, in-hospital mortality, and healthcare burden (2017-2022)

  • by Rocío López Herrero, Paula Martínez-Jiménez, Daniel Ortiz del Olmo, Rosa Dolores Prieto-Utrera, Rosa Cobo-Zubia, Adrián García- Concejo, Mario Lorenzo-López, Irina Rebollo-Mato, Fernando Vaquerizo-Villar, Rodrigo Poves-Álvarez, Esther Gómez-Sánchez, Eduardo Tamayo

  • September 25, 2026

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