Electroacupuncture as an eosinophil-targeting treatment in ovalbumin-induced allergic rhinitis involving β2-adrenergic receptor in a mouse model - Takeaways - MDSpire

Electroacupuncture as an eosinophil-targeting treatment in ovalbumin-induced allergic rhinitis involving β2-adrenergic receptor in a mouse model

  • By

  • Tran Van Bao Quach

  • Thanh-Hien Vu Nguyen

  • Ngoc Chi Lan Nguyen

  • Che-Hsuan Lin

  • Yi-Hung Chen

  • June 16, 2026

  • 0 min

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  • 1

    Electroacupuncture (EA) significantly alleviated nasal symptoms in a mouse model of allergic rhinitis, comparable to the antihistamine chlorpheniramine.

  • 2

    EA reduced eosinophilic inflammation and associated biomarkers, while chlorpheniramine primarily suppressed mast cell degranulation.

  • 3

    Pre-treatment with a β2-adrenergic antagonist abolished the beneficial effects of EA on eosinophilic inflammation and cytokine levels.

  • 4

    EA was associated with increased plasma norepinephrine and epinephrine levels, indicating a potential neuroimmune mechanism.

  • 5

    The study suggests that EA may represent a complementary intervention for eosinophil-driven allergic rhinitis through β2-adrenergic receptor modulation.

Original Source(s)

Electroacupuncture as an eosinophil-targeting treatment in ovalbumin-induced allergic rhinitis involving β2-adrenergic receptor in a mouse model

  • by Tran Van Bao Quach, Thanh-Hien Vu Nguyen, Ngoc Chi Lan Nguyen, Che-Hsuan Lin, Yi-Hung Chen

  • June 16, 2026

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