Cognitive-motor network integration as a behavioral marker of cognitive reserve in post-stroke rehabilitation - Takeaways - MDSpire

Cognitive-motor network integration as a behavioral marker of cognitive reserve in post-stroke rehabilitation

  • By

  • Katharina Kreiger

  • Elisabeth Weiss

  • Felix Fluri

  • June 9, 2026

  • 0 min

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  • 1

    Cognitive reserve is a key determinant of recovery potential after stroke, operationalized through network-based approaches.

  • 2

    Cognitive leisure activities were identified as the strongest predictor of rehabilitation response in stroke patients.

  • 3

    Responders to rehabilitation did not show significantly higher baseline cognitive scores compared to non-responders.

  • 4

    Network analyses revealed that responders had a more integrated cognitive-motor architecture at admission.

  • 5

    The study supports a network-based conceptualization of cognitive reserve with implications for rehabilitation strategies.

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