Assessment of Liver Cancer Burden from 1990 to 2021 with Projections for 2040: Findings from the 2021 Global Burden of Disease Study - Takeaways - MDSpire

Assessment of Liver Cancer Burden from 1990 to 2021 with Projections for 2040: Findings from the 2021 Global Burden of Disease Study

  • By

  • Yong Xie

  • Tianshi Lyu

  • Haitao Guan

  • Li Song

  • Xiaoqiang Tong

  • Yinghua Zou

  • Min Yang

  • Jian Wang

  • April 29, 2026

  • 0 min

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  • 1

    Liver cancer poses a significant global health threat, with increasing incidence and mortality rates projected through 2040.

  • 2

    In 2021, hepatitis B virus-related liver cancer had the highest burden, with 1,031,830 incident cases globally.

  • 3

    The 65–69 age group experienced the heaviest liver cancer burden, predominantly from hepatitis B virus-related cases.

  • 4

    Higher sociodemographic indices correlate with greater liver cancer burden, particularly in high-income Asia Pacific and East Asia.

  • 5

    Projections indicate a 51.97% increase in non-alcoholic steatohepatitis-related liver cancer cases by 2040, highlighting urgent public health needs.

Original Source(s)

Assessment of Liver Cancer Burden from 1990 to 2021 with Projections for 2040: Findings from the 2021 Global Burden of Disease Study

  • by Yong Xie, Tianshi Lyu, Haitao Guan, Li Song, Xiaoqiang Tong, Yinghua Zou, Min Yang, Jian Wang

  • April 29, 2026

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