Effectiveness of Prophylactic Doses of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery: A Systematic Review and Meta-Analysis - Takeaways - MDSpire

Effectiveness of Prophylactic Doses of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery: A Systematic Review and Meta-Analysis

  • By

  • Pedro Bicudo Bregion

  • Josélio Rodrigues de Oliveira-Filho

  • Victor Kenzo Ivano

  • Everton Cazzo

  • February 21, 2026

  • 0 min

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  • 1

    Bariatric surgery, particularly sleeve gastrectomy, is effective for obesity but poses risks of postoperative bleeding and complications.

  • 2

    Tranexamic acid has emerged as a potential adjunct for controlling hemorrhage in bariatric surgery, showing promising outcomes in recent studies.

  • 3

    The updated systematic review incorporates new studies and subgroup analyses to evaluate the efficacy and safety of tranexamic acid in bariatric procedures.

  • 4

    Primary outcomes assessed include changes in hemoglobin levels, intraoperative bleeding, length of stay, and operative time in patients receiving tranexamic acid.

  • 5

    Statistical analyses utilized random-effects models to account for clinical heterogeneity, with publication bias evaluated through funnel plots.

Original Source(s)

Effectiveness of Prophylactic Doses of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery: A Systematic Review and Meta-Analysis

  • by Pedro Bicudo Bregion, Josélio Rodrigues de Oliveira-Filho, Victor Kenzo Ivano, Everton Cazzo

  • February 21, 2026

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