Giant cell tumor of the pubic bone with concomitant enchondroma: a case report - Takeaways - MDSpire

Giant cell tumor of the pubic bone with concomitant enchondroma: a case report

  • By

  • Hongjing Sun

  • Minghao Gao

  • Hong Yu

  • Xiaohui Feng

  • May 12, 2026

  • 0 min

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  • 1

    Giant cell tumor of bone (GCTB) is a locally aggressive neoplasm, comprising 4%-5% of primary bone tumors, often affecting the metaphysis of long bones.

  • 2

    Enchondroma is a benign cartilaginous tumor, commonly found in short tubular bones, and its occurrence alongside GCTB in the pubic bone is exceedingly rare.

  • 3

    A 36-year-old female presented with left hip pain, and imaging revealed an osteolytic lesion in the left pubic bone indicative of GCTB.

  • 4

    Histopathological analysis confirmed the coexistence of GCTB and enchondroma, with GCTB showing high aggressive potential and intravascular tumor thrombi.

  • 5

    This case emphasizes the importance of histopathological assessment in diagnosing unusual tumor combinations and their clinical implications.

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