Comparison of Two AI Chatbots for Diagnosis and Providing Treatment Suggestions in Retinopathy of Prematurity: Retrospective Study - Takeaways - MDSpire
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A Retrospective Comparison of Two AI Chatbots’ Diagnostic Accuracy and Treatment Recommendations for Retinopathy of Prematurity

  • By

  • Shaojuan Peng

  • Xinyu Zhao

  • Zhenquan Wu

  • Duo Yuan

  • Na Duan

  • Kaixuan Cui

  • Zhen Yu

  • Weihua Yang

  • Wenbin Wei

  • Wei Chi

  • Guoming Zhang

  • October 7, 2026

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  • 1

    Retinopathy of prematurity is a major cause of preventable childhood blindness, and its burden has increased alongside survival among low-birth-weight infants.

  • 2

    A worldwide shortage of experienced pediatric ophthalmologists has intensified as ROP screening and treatment needs expand, particularly in resource-limited regions.

  • 3

    ROP diagnosis and treatment recommendations depend on accurate assessment of retinal vascular and lesion characteristics under ICROP3.

  • 4

    Wide-field fundus imaging provides objective evidence of avascular retinal area and morphology that informs interventions such as laser therapy and anti-VEGF injection.

  • 5

    The study retrospectively compares two AI chatbots’ diagnostic accuracy and treatment recommendations for ROP.

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