Initial non-surgical versus upfront surgical management of ERCP-related perforations by Stapfer type: a systematic review and meta-analysis - Takeaways - MDSpire
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Initial Conservative Versus Early Surgical Treatment of ERCP-Related Perforations by Stapfer Classification: A Systematic Review and Meta-Analysis

  • By

  • Eyad Jamileh

  • Omar Farooq

  • Mohamed Xamza

  • Daren Subar

  • Joel Lambert

  • October 13, 2026

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  • 1

    ERCP-related perforations are classified by Stapfer type according to injury site and mechanism, with clinical course and intervention needs varying across types.

  • 2

    The review compared outcomes by initial management strategy, retaining patients who later required rescue surgery in the initial non-surgical group as treatment failures.

  • 3

    Initial non-surgical management included conservative care, endoscopic intervention, and/or image-guided drainage; upfront surgery was the initial definitive operative approach.

  • 4

    The primary outcome was success of the initial strategy, defined as survival to hospital discharge without rescue surgery after non-surgical management or after upfront surgery.

  • 5

    The review assessed outcomes overall and by Stapfer type, but sparse surgical comparator data for Types III and IV precluded meaningful estimates of relative effects.

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