The Right Atrium and Atrialised Right Ventricle are Associated with Cardiac Output During Exercise in Patients with Ebstein Anomaly of the Tricuspid Valve - Takeaways - MDSpire

The Right Atrium and Atrialised Right Ventricle are Associated with Cardiac Output During Exercise in Patients with Ebstein Anomaly of the Tricuspid Valve

  • By

  • Ganesh Kumar Gnanappa

  • Jack Luxford

  • Laura Dryburgh

  • David S. Celermajer

  • Rajesh Puranik

  • Karina Laohachai

  • Julian Ayer

  • July 15, 2026

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  • 1

    Ebstein anomaly is characterized by tricuspid valve displacement, atrialisation of the right ventricle, and tricuspid regurgitation.

  • 2

    Exercise capacity in patients with Ebstein anomaly is linked to echocardiographic and cardiac MRI parameters of disease severity.

  • 3

    The study evaluated cardiac output during exercise in un-operated patients with Ebstein anomaly using cardio-pulmonary exercise testing and cardiac MRI.

  • 4

    Thirteen un-operated patients with Ebstein anomaly participated in the study, which adhered to ethical guidelines and received institutional approval.

  • 5

    Cardiac index was calculated from aortic and pulmonary artery flow data at rest and during exercise to assess cardiac performance.

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