Microembolic signals in transcranial Doppler and the functional outcome of patients with acute ischemic stroke: a meta-analysis - Takeaways - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Transcranial Doppler Detection of Microembolic Signals and Their Prognostic Impact on Functional Outcomes in Acute Ischemic Stroke: A Meta-Analysis

  • By

  • Jun Qiao

  • Zhikun Zhang

  • Yujin Feng

  • Yi Wang

  • September 10, 2026

Share

  • 1

    Transcranial Doppler ultrasonography can detect microembolic signals (MES), which indicate ongoing cerebral embolization in acute ischemic stroke patients.

  • 2

    A meta-analysis of 13 cohort studies with 1,777 patients found that MES presence significantly correlates with poor functional outcomes after acute ischemic stroke.

  • 3

    The odds ratio for poor functional outcomes associated with MES was 2.85, indicating a strong association without significant heterogeneity among studies.

  • 4

    Subgroup analyses showed consistent results across different study designs and patient characteristics, with no significant modifiers of the association.

  • 5

    Further research is needed to confirm the independent prognostic value of MES beyond established clinical and imaging predictors in acute ischemic stroke.

Original Source(s)

Microembolic signals in transcranial Doppler and the functional outcome of patients with acute ischemic stroke: a meta-analysis

  • by Jun Qiao, Zhikun Zhang, Yujin Feng, Yi Wang

  • September 10, 2026

Related Content

Correction: Association of infarct volume with early neurological deterioration in ischemic stroke patients undergoing endovascular treatment

Baptist Health Brain & Spine Care to Host 14th Annual Miami Neuroscience Symposium Nov. 4-6, Bringing Leading Experts Together to Explore Advances in Brain and Spine Care

Baptist Health will bring together leading physicians, researchers and healthcare professionals from South Florida and across the country for the 14th Annual Baptist Health Miami Neuroscience Symposium, taking place Nov. 4-6, 2026, at Hilton Miami Dadeland and virtually via Zoom.

  • by

  • August 21, 2026

  • 5 min
Completion rate and safety of non-invasive brain stimulation for upper limb dysfunction after stroke: a systematic review and network meta-analysis