Biologics Commonly Used in Cutaneous Crohn's Disease
Retrospective multicenter cohort highlights genital-predominant presentation patterns and frequent combination therapy use in cutaneous Crohn's disease.
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By
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Andrea Surnit
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May 27, 2026
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1
A retrospective study found that most patients with cutaneous Crohn disease improved after receiving biologic or small-molecule inhibitor therapy.
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The study reviewed data from 57 patients, with 81% being female and a mean diagnosis age of 37 years.
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Genital involvement was the most common cutaneous presentation, occurring in 44% of patients.
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Tumor necrosis factor alpha inhibitors were the most frequently prescribed biologics, used in 85% of treated patients.
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The study's limitations include its uncontrolled design and variability in treatment regimens across institutions.