Do acute postoperative seizures predict epilepsy surgery outcome? a scoping review - Takeaways - MDSpire

Do acute postoperative seizures predict epilepsy surgery outcome? a scoping review

  • By

  • Sebastiaan E. A. van Maanen

  • Maeike J. M. Zijlmans

  • Pieter van Eijsden

  • Sandra M. A. van der Salm

  • March 13, 2025

  • 0 min

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  • 1

    Resective surgery is the preferred treatment for epilepsy, with 61% of children and 56% of adults achieving seizure freedom postoperatively.

  • 2

    Acute postoperative seizures (APOS) occur within the first week after surgery and are linked to long-term seizure recurrence.

  • 3

    Up to 40% of patients with APOS may experience favorable long-term outcomes, indicating diverse disease courses.

  • 4

    Differentiating between running-down seizures (RDS) and running-up seizures (RUS) is crucial for clinical decision-making.

  • 5

    Identifying predictors for RDS and RUS can improve patient outcomes and reduce unnecessary treatment burdens.

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