Spontaneous ovarian hyperstimulation syndrome in early singleton pregnancy with hepatic involvement: two case reports of atypical presentations - Takeaways - MDSpire

Spontaneous ovarian hyperstimulation syndrome in early singleton pregnancy with hepatic involvement: two case reports of atypical presentations

  • By

  • M. J. Nuñez Burbano

  • Sergio Andrés Escobar

  • Dayanna Pinto-Martínez

  • Víctor S. Rangel

  • Ricardo García Yepes

  • Yaisa Maritza Castaño Toro

  • Jorge L. Campo

  • June 24, 2026

  • 0 min

Share

  • 1

    Spontaneous ovarian hyperstimulation syndrome (OHSS) is rare in singleton pregnancies and may present with atypical systemic manifestations, including hepatic involvement.

  • 2

    Two cases of spontaneous OHSS with liver complications were reported, involving a 21-year-old and a 23-year-old woman with abdominal symptoms and elevated liver enzymes.

  • 3

    Imaging in both cases revealed enlarged ovaries and cholelithiasis, while other causes of liver dysfunction were excluded through comprehensive workups.

  • 4

    Management of the cases was conservative, involving close clinical follow-up, although one patient required laparoscopic cholecystectomy for symptomatic biliary disease.

  • 5

    These cases suggest that spontaneous OHSS should be considered in pregnant patients with abdominal symptoms and abnormal liver function tests, even without assisted reproduction.

Original Source(s)

Spontaneous ovarian hyperstimulation syndrome in early singleton pregnancy with hepatic involvement: two case reports of atypical presentations

  • by M. J. Nuñez Burbano, Sergio Andrés Escobar, Dayanna Pinto-Martínez, Víctor S. Rangel, Ricardo García Yepes, Yaisa Maritza Castaño Toro, Jorge L. Campo

  • June 24, 2026

Related Content

Artificial intelligence in intimate partner violence risk pathways: a PRISMA-ScR review of femicide prevention and medico-legal accountability

Functional shifts in immune composition follow lactation stage in human milk

Beta-2 Agonists Tied to ASD Risk?

Systematic review of 8 observational studies found limited evidence on associations between prenatal asthma-medication exposure and neurodevelopmental outcomes, with autism spectrum disorder the only outcome suitable for meta-analysis.