Prognostic Factors for Patients Under 45 Undergoing Surgery for Colorectal Liver Metastases: A SEER Population-Based Study - Takeaways - MDSpire
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Prognostic Indicators for Surgical Patients Under 45 with Colorectal Liver Metastases: Insights from a SEER Population Analysis

  • By

  • Gabrielle Grob

  • Fang Fang

  • Matvey Karpov

  • Eric Feliberti

  • Marybeth Hughes

  • Rachel Burke

  • Winifred Lo

  • June 18, 2026

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  • 1

    The incidence of colorectal cancer has increased among adults under 50, who often present with metastatic disease.

  • 2

    Surgical resection is a potentially curative option for approximately one-third of patients with isolated colorectal liver metastases.

  • 3

    The study analyzed 2222 patients, comparing those under 45 years old with those 45 years and older regarding survival outcomes.

  • 4

    Younger patients showed a median overall survival of 61 months, compared to 49 months for older patients.

  • 5

    Higher household income and lower nodal disease burden were associated with better disease-specific survival in older patients.

Original Source(s)

Prognostic Factors for Patients Under 45 Undergoing Surgery for Colorectal Liver Metastases: A SEER Population-Based Study

  • by Gabrielle Grob, Fang Fang, Matvey Karpov, Eric Feliberti, Marybeth Hughes, Rachel Burke, Winifred Lo

  • June 18, 2026

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