Combined Immunity from Infection and Vaccination Against Confirmed SARS-CoV-2 Infections in a European Multi-Center Prospective Study of Healthcare Workers, 2021–2024 - Takeaways - MDSpire

Combined Immunity from Infection and Vaccination Against Confirmed SARS-CoV-2 Infections in a European Multi-Center Prospective Study of Healthcare Workers, 2021–2024

  • By

  • Madelyn Rojas-Castro

  • Ranya Mulchandani

  • Kim Brolin

  • Zvjezdana Lovrić Makarić

  • Anneli Uusküla

  • Colm Bergin

  • Catherine Fleming

  • Paolo Bonfanti

  • Rita Murri

  • Viesturs Zvirbulis

  • Dace Zavadska

  • Konstanty Szuldrzynski

  • Vânia Gaio

  • Corneliu Petru Popescu

  • Mihai Craiu

  • Raluca-Maria Hrișcă

  • Maria Cisneros

  • Miriam Latorre-Millán

  • Goranka Petrović

  • Liss Lohur

  • Jonathan McGrath

  • Lauren Ferguson

  • Anna Spolti

  • Katleen De Gaetano Donati

  • Ilze Abolina

  • Dagne Gravele

  • Ausenda Machado

  • Simin Aysel Florescu

  • Mihaela Lazar

  • Pilar Subirats

  • Laura Clusa

  • Gordan Sarajlić

  • Jacklyn Sui

  • Claire Kenny

  • Rosaria Santangelo

  • Dainis Krievins

  • Elza Anna Barzdina

  • Camila Valadas Henriques

  • Alma Gabriela Kosa

  • Săftica-Mariana Pohrib

  • Victor Daniel Miron

  • Carmen Muñoz-Almagro

  • Ana Maria Milagro

  • Sabrina Bacci

  • Camelia Savulescu

  • December 29, 2025

  • 0 min

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  • 1

    Hybrid immunity from prior SARS-CoV-2 infection and vaccination provides significant protection against COVID-19 among healthcare workers.

  • 2

    Healthcare workers were prioritized for COVID-19 vaccination to reduce disease burden and prevent transmission to vulnerable patients.

  • 3

    The study analyzed hybrid immunity during periods of predominant Omicron sub-lineages among healthcare workers across nine European countries.

  • 4

    Vaccination strategies evolved from initial booster doses to seasonal vaccinations targeting high-risk groups in response to emerging variants.

  • 5

    Real-world evidence on hybrid immunity's effectiveness in the post-pandemic era remains limited, highlighting the need for ongoing research.

Original Source(s)

Combined Immunity from Infection and Vaccination Against Confirmed SARS-CoV-2 Infections in a European Multi-Center Prospective Study of Healthcare Workers, 2021–2024

  • by Madelyn Rojas-Castro, Ranya Mulchandani, Kim Brolin, Zvjezdana Lovrić Makarić, Anneli Uusküla, Colm Bergin, Catherine Fleming, Paolo Bonfanti, Rita Murri, Viesturs Zvirbulis, Dace Zavadska, Konstanty Szuldrzynski, Vânia Gaio, Corneliu Petru Popescu, Mihai Craiu, Raluca-Maria Hrișcă, Maria Cisneros, Miriam Latorre-Millán, Goranka Petrović, Liss Lohur, Jonathan McGrath, Lauren Ferguson, Anna Spolti, Katleen De Gaetano Donati, Ilze Abolina, Dagne Gravele, Ausenda Machado, Simin Aysel Florescu, Mihaela Lazar, Pilar Subirats, Laura Clusa, Gordan Sarajlić, Jacklyn Sui, Claire Kenny, Rosaria Santangelo, Dainis Krievins, Elza Anna Barzdina, Camila Valadas Henriques, Alma Gabriela Kosa, Săftica-Mariana Pohrib, Victor Daniel Miron, Carmen Muñoz-Almagro, Ana Maria Milagro, Sabrina Bacci, Camelia Savulescu

  • December 29, 2025

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