Does Local Excision Without Salvage Surgery Affect the Prognostic Outcome of Patients With Malignant Colorectal Polyp? A Long-Term Survival Analysis - Takeaways - MDSpire
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Impact of Local Excision Without Salvage Surgery on Prognosis in Patients with Malignant Colorectal Polyps: A Long-Term Survival Study

  • By

  • Vienna Man Wah Ng

  • Simon Chu

  • Anson Huen Yan Chan

  • Sok Fei Hon

  • Simon Siu Man Ng

  • June 23, 2026

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  • 1

    Colorectal cancer was the third most common cancer globally in 2022, with a projected increase to 3.2 million new cases annually by 2040.

  • 2

    T1 malignant polyps diagnosed post-endoscopic removal account for 40%-60% of stage I colorectal cancer, with varying risks of metastasis and recurrence.

  • 3

    Clinical guidelines recommend additional surgery for high-risk histopathological features, yet over 80% of such patients may not have lymph node metastasis.

  • 4

    Local excision techniques, such as ESD and TAMIS, are considered curative for early colorectal cancer, with studies suggesting safe conservative management.

  • 5

    The study aims to evaluate long-term survival outcomes in patients with malignant colorectal polyps treated with local excision without salvage surgery.

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