Tao-Hong-Si-Wu-Tang protects against methionine- and choline-deficient diet-induced hepatic steatosis in rats and is associated with inhibition of oxidative stress, inflammation, apoptosis, and pyroptosis - Takeaways - MDSpire

Tao-Hong-Si-Wu-Tang protects against methionine- and choline-deficient diet-induced hepatic steatosis in rats and is associated with inhibition of oxidative stress, inflammation, apoptosis, and pyroptosis

  • By

  • Luyao Xu

  • Qiuling Li

  • Chengqin Lu

  • Mincheng Zheng

  • Wenhai Guo

  • Yun Chen

  • Jiaying Dai

  • Yao Deng

  • Ning Zhang

  • Kanlin Yang

  • Xinling Chen

  • Kangrong Wang

  • Guohang Yan

  • Hantao Li

  • Rui Duan

  • Jiean Xu

  • Wei Liu

  • Hongzhi Yang

  • Jinwen Xu

  • Min Dai

  • Yaxing Zhang

  • July 6, 2026

  • 0 min

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  • 1

    Tao-Hong-Si-Wu-Tang (THSWT) is a traditional Chinese medicine formula with anti-oxidation, anti-inflammation, and anti-apoptosis properties.

  • 2

    THSWT treatment significantly alleviated hepatic steatosis in rats fed a methionine- and choline-deficient diet.

  • 3

    The optimal dosage of THSWT for treatment was determined to be 2.5 g/kg/day.

  • 4

    THSWT treatment reduced oxidative stress markers and pro-inflammatory cytokines in the liver of treated rats.

  • 5

    The study suggests THSWT may be a candidate for further exploration in treating hepatic steatosis.

Original Source(s)

Tao-Hong-Si-Wu-Tang protects against methionine- and choline-deficient diet-induced hepatic steatosis in rats and is associated with inhibition of oxidative stress, inflammation, apoptosis, and pyroptosis

  • by Luyao Xu, Qiuling Li, Chengqin Lu, Mincheng Zheng, Wenhai Guo, Yun Chen, Jiaying Dai, Yao Deng, Ning Zhang, Kanlin Yang, Xinling Chen, Kangrong Wang, Guohang Yan, Hantao Li, Rui Duan, Jiean Xu, Wei Liu, Hongzhi Yang, Jinwen Xu, Min Dai, Yaxing Zhang

  • July 6, 2026

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