Progression of Coronary Calcium Detected on Routine Chest CT Enhances Cardiovascular Risk Assessment in Individuals with Inflammatory Bowel Disease: Findings from a Multicenter Study - Takeaways - MDSpire

Progression of Coronary Calcium Detected on Routine Chest CT Enhances Cardiovascular Risk Assessment in Individuals with Inflammatory Bowel Disease: Findings from a Multicenter Study

  • By

  • Qi Zhang

  • Yanxun Su

  • Chenyao Song

  • Ting Xu

  • Wenyan Liu

  • Jiaxin Cao

  • Binwei Guo

  • Lingjie Wang

  • Huajie Yue

  • Cheng Xu

  • Xuhui Zhao

  • Sijin Li

  • April 17, 2026

  • 0 min

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  • 1

    Coronary artery calcium (CAC) progression significantly predicts major adverse cardiovascular events (MACE) in patients with inflammatory bowel disease (IBD).

  • 2

    In a study of 467 IBD patients, 27.6% exhibited CAC progression, correlating with increased cardiovascular risk and incident atrial fibrillation.

  • 3

    Adding CAC progression to traditional cardiovascular risk factors improved risk stratification, enhancing the C-index from 0.67 to 0.73.

  • 4

    Baseline CAC provided limited prognostic value, with a minimal increase in C-index from 0.67 to 0.68, highlighting the importance of CAC progression.

  • 5

    The findings support the need for improved cardiovascular risk assessment tools for IBD patients, as conventional methods may underestimate their risk.

Original Source(s)

Progression of Coronary Calcium Detected on Routine Chest CT Enhances Cardiovascular Risk Assessment in Individuals with Inflammatory Bowel Disease: Findings from a Multicenter Study

  • by Qi Zhang, Yanxun Su, Chenyao Song, Ting Xu, Wenyan Liu, Jiaxin Cao, Binwei Guo, Lingjie Wang, Huajie Yue, Cheng Xu, Xuhui Zhao, Sijin Li

  • April 17, 2026

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