-
1
Microglia exhibit significant heterogeneity in autism spectrum disorder (ASD), influenced by region, developmental stage, and sex.
-
2
Current evidence suggests that ASD-related microglial alterations are context-dependent and cannot be reduced to a single inflammatory phenotype.
-
3
Immunometabolic processes, including lipid handling and mitochondrial function, play a crucial role in microglial competence in ASD.
-
4
Microglia interact with astrocytes and other cell types, complicating the interpretation of microglial signals in ASD.
-
5
Research emphasizes the need for precise interpretations of microglial biology in ASD, avoiding non-specific inflammatory labels.
