A prehabilitation-enhanced nomogram for predicting early pulmonary recovery failure after lung tumor surgery: development and multicenter validation - Takeaways - MDSpire

A prehabilitation-enhanced nomogram for predicting early pulmonary recovery failure after lung tumor surgery: development and multicenter validation

  • By

  • Sanhua Lian

  • Xihua Lian

  • Zhixing Zhu

  • Chunping Shi

  • Fengyu Chen

  • July 13, 2026

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  • 1

    A prehabilitation-enhanced nomogram was developed to predict early postoperative pulmonary recovery failure after lung tumor surgery.

  • 2

    The study utilized a multicenter retrospective design with a development cohort and an external validation cohort.

  • 3

    Five predictors were included in the final nomogram: intraoperative blood loss, DLCO% predicted, preoperative resting SpO2, and two target-achieved days.

  • 4

    The nomogram demonstrated improved discrimination, with AUCs increasing significantly across training and validation cohorts.

  • 5

    Calibration was acceptable, and decision curve analysis indicated the nomogram's clinical usefulness for risk stratification.

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