Lung transplantation from polytrauma donors: beyond primary graft dysfunction

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Polytrauma donors (PD) are younger and have fewer comorbidities compared to non-polytrauma donors (NPD), making them a potentially valuable resource for lung transplantation.
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The study analyzed 125 lung transplant recipients, comparing outcomes between PD (n=36) and NPD (n=89) groups over early and mid-term periods.
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Early postoperative outcomes, including primary graft dysfunction (PGD) and ICU stay, were comparable between PD and NPD groups.
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At 6 months, overall survival was higher in the PD group (91.7%) compared to the NPD group (75.3%), with statistical significance (p=0.048).
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After propensity score matching, no significant differences were found in survival, perioperative outcomes, or pulmonary function between PD and NPD groups.

Frontiers In Medicine

by Chiara Catelli, Daniele Marianello, Andrea Lloret Madrid, Marianna Rizzo, Miriana D'Alessandro, Margherita Sambo, Francesca Montagnani, Marco Guerrieri, David Bennett, Elena Bargagli, Piero Paladini, Federico Franchi, Luca Luzzi
June 19, 2026

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