Medically Assisted Reproduction and Hormone-Related Cancers - Takeaways - MDSpire

Medically Assisted Reproduction and Hormone-Related Cancers

  • By

  • Adrian Raymond Walker

  • Christos Venetis

  • Signe Opdahl

  • Antoinette C. Anazodo

  • Neville F. Hacker

  • Michael Chapman

  • Louisa Jorm

  • Robert J. Norman

  • Catharyn Stern

  • Ursula M. Sansom-Daly

  • Georgina Mary Chambers

  • Claire Melissa Vajdic

  • July 13, 2026

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  • 1

    Medically assisted reproduction (MAR) includes treatments that help individuals achieve pregnancy, with approximately 3 million ART cycles performed annually worldwide.

  • 2

    MAR treatments often involve hormonal medications, raising concerns about potential associations with hormone-related cancers, including breast and ovarian cancers.

  • 3

    Recent meta-analyses indicate few to no significant associations between ART and hormone-related cancer risk, despite variability in study designs and confounder adjustments.

  • 4

    Some studies reported specific associations between ART and increased risks of invasive breast cancer and ovarian cancer, particularly in certain populations.

  • 5

    This study employs a retrospective emulated target trial design to analyze the relationship between MAR and hormone-related cancers, utilizing linked anonymized data.

Original Source(s)

Medically Assisted Reproduction and Hormone-Related Cancers

  • by Adrian Raymond Walker, Christos Venetis, Signe Opdahl, Antoinette C. Anazodo, Neville F. Hacker, Michael Chapman, Louisa Jorm, Robert J. Norman, Catharyn Stern, Ursula M. Sansom-Daly, Georgina Mary Chambers, Claire Melissa Vajdic

  • July 13, 2026

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