TyG index predicts adverse cardiovascular outcomes in patients with multimorbidity of hypertension and obstructive coronary artery disease: a cohort study - Takeaways - MDSpire
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Triglyceride-Glucose Index as a Predictor of Negative Cardiovascular Outcomes in Patients with Hypertension and Obstructive Coronary Artery Disease: Findings from a Cohort Study

  • By

  • Qingying Jiao

  • Mengmeng Wang

  • Zishan Liu

  • Zhiyi Yu

  • Guixia Sun

  • Jiachao Xu

  • Tianqi Teng

  • Yanyan Du

  • Zihan Dong

  • Yongqi Shan

  • Jingjing Zhang

  • Zihan Sun

  • Haichu Yu

  • July 16, 2026

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  • 1

    The study involved 1,024 individuals with essential hypertension and obstructive coronary artery disease treated at The Affiliated Hospital of Qingdao University.

  • 2

    After 2 years, 19.73% of patients experienced major adverse cardiovascular events, with a significant link to the triglyceride-glucose index.

  • 3

    Each one-unit increase in the triglyceride-glucose index was associated with a 45.2% increased risk of major adverse cardiovascular events.

  • 4

    Subgroup analysis confirmed the triglyceride-glucose index's consistent predictive performance across different patient groups.

  • 5

    Mendelian randomization analysis indicated a significant causal relationship between elevated triglyceride-glucose index and adverse cardiovascular outcomes.

Original Source(s)

TyG index predicts adverse cardiovascular outcomes in patients with multimorbidity of hypertension and obstructive coronary artery disease: a cohort study

  • by Qingying Jiao, Mengmeng Wang, Zishan Liu, Zhiyi Yu, Guixia Sun, Jiachao Xu, Tianqi Teng, Yanyan Du, Zihan Dong, Yongqi Shan, Jingjing Zhang, Zihan Sun, Haichu Yu

  • July 16, 2026

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