Safety signals of perfluorohexyloctane ophthalmic solution in patients with dry eye disease - Takeaways - MDSpire

Safety signals of perfluorohexyloctane ophthalmic solution in patients with dry eye disease

  • By

  • Zhengtai Sun

  • Yuting Liu

  • Lijuan Que

  • May 28, 2026

  • 0 min

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  • 1

    The study evaluated the safety of perfluorohexyloctane ophthalmic solution for dry eye disease using the FDA Adverse Event Reporting System (FAERS) database.

  • 2

    A total of 92 adverse event reports were identified, with the most common issues being product delivery mechanism problems and eye irritation.

  • 3

    The top adverse events meeting positive signal criteria included wrong dose and patient dissatisfaction with treatment.

  • 4

    The median time-to-onset for adverse events related to perfluorohexyloctane was 2 days.

  • 5

    FAERS data did not indicate major safety concerns, with reported adverse events primarily linked to the instillation process.

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