Infection risk reduction with povidone-iodine rectal disinfection prior to transrectal prostate biopsy: an updated systematic review and meta-analysis

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Transrectal ultrasound-guided prostate biopsy (TRUS-PB) has a high incidence of infectious complications, reported up to 6.3%.
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Povidone-iodine (PI) rectal disinfection is recommended by EAU guidelines to reduce infectious complications before TRUS-PB.
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This systematic review and meta-analysis aimed to evaluate the efficacy of PI plus antibiotic prophylaxis (AP) compared to AP monotherapy.
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Ten randomized controlled trials involving 3,297 patients were included, focusing on fever and sepsis as primary outcomes.
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Statistical analyses indicated the need for further investigation into the comparative efficacy of PI with AP versus AP alone.

World Journal Of Urology

by Ichiro Tsuboi, Akihiro Matsukawa, Mehdi Kardoust Parizi, Jakob Klemm, Stefano Mancon, Sever Chiujdea, Tamás Fazekas, Ekaterina Laukhtina, Tatsushi Kawada, Satoshi Katayama, Takehiro Iwata, Kensuke Bekku, Koichiro Wada, Motoo Araki, Shahrokh F. Shariat
April 23, 2024

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