Blood pressure can be seriously elevated during botulinum toxin A detrusor injection - Takeaways - MDSpire

Blood pressure can be seriously elevated during botulinum toxin A detrusor injection

  • By

  • Heinrich Schulte-Baukloh

  • Catarina Weiss

  • Burkert Pieske

  • Thorsten Schlomm

  • Bernhard Ralla

  • Hendrik Borgmann

  • Dirk Höppner

  • Sarah Weinberger

  • April 3, 2025

  • 0 min

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  • 1

    Onabotulinumtoxin A detrusor injection is used for overactive bladder after conservative therapies fail.

  • 2

    Real-world data on the efficacy and safety of OnabotA treatment for OAB is limited, despite promising clinical trial results.

  • 3

    Elevated blood pressure and heart rate were monitored during OnabotA injections to assess cardiovascular risk.

  • 4

    Patients with resting blood pressure above 190 mmHg were excluded from OnabotA injections and referred for cardiology evaluation.

  • 5

    The study included 70 female patients, primarily with idiopathic OAB, to evaluate hemodynamic changes during the procedure.

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