Temporal trends in clinical and inflammatory features of Kawasaki disease across the COVID-19 pandemic: a single-center experience from Turkey - Takeaways - MDSpire

Temporal trends in clinical and inflammatory features of Kawasaki disease across the COVID-19 pandemic: a single-center experience from Turkey

  • By

  • Gamze Vuran

  • Murat Muhtar Yılmazer

  • July 15, 2026

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  • 1

    This study analyzed 87 children diagnosed with Kawasaki disease across three periods: pre-pandemic, pandemic, and post-pandemic.

  • 2

    During the pandemic, patients exhibited higher C-reactive protein and erythrocyte sedimentation rates, with increased thrombocytosis and decreased cervical lymphadenopathy.

  • 3

    In the post-pandemic period, time to diagnosis was shorter, more clinical findings were present at diagnosis, and liver transaminase elevations were more frequent.

  • 4

    Rates of intravenous immunoglobulin resistance, hospital stay length, coronary artery involvement, and valvular regurgitation remained similar across all periods.

  • 5

    The study suggests that the COVID-19 pandemic influenced the inflammatory and clinical characteristics of Kawasaki disease without affecting cardiac outcomes.

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