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1
The study identified symptom clusters and sentinel symptoms in colorectal cancer patients undergoing post-operative adjuvant chemotherapy.
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2
A total of 220 patients were recruited, with 182 completing follow-ups, resulting in a 12.50% loss-to-follow-up rate.
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3
Symptom burden increased from an average of 8.32 symptoms at T1 to 13.3 at T3, with fatigue, decreased appetite, and disturbed sleep being the most prevalent.
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4
Symptom clusters evolved from three at T1 to four at T2 and T3, with a distinct fatigue-pain cluster emerging.
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5
Seven sentinel symptoms were identified, including taste changes, nausea, and disturbed sleep, which may inform future symptom management strategies.
