Does corneal structure remain stable after 10 years of contact lenses?

Researchers found comparable corneal thickness and most endothelial measures in those who began wearing daily disposable hydrogel lenses during childhood, although localized cell size differences emerged.

By
Andrea Surnit
November 2, 2026
4 min

MDSpire News

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In a cross-sectional study, 42 young adults who had worn daily disposable omafilconA hydrogel lenses since childhood were compared with age-matched nonwearers.
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After an average of 11 years of lens wear, corneal epithelial and stromal thickness did not differ significantly between groups across the measured regions.
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Endothelial cell density and hexagonality were comparable between groups, but cell-size variation was significantly greater in the superior and superonasal regions among lens wearers.
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Researchers reported no ocular adverse events among contact lens wearers during the preceding 10 years.
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The cross-sectional design, small sample, limited measurement area, and use of one lens type and replacement schedule limit the study’s generalizability.

Does corneal structure remain stable after 10 years of contact lenses?

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Original Source(s)

Does corneal structure remain stable after 10 years of contact lenses?

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