Prognostic nutritional index, but not NLR or PLR, is linked to survival in multiple myeloma - Takeaways - MDSpire

Prognostic nutritional index, but not NLR or PLR, is linked to survival in multiple myeloma

  • By

  • Nermin Keni Begendi

  • Mustafa Duran

  • Yaşar Culha

  • May 28, 2026

  • 0 min

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  • 1

    The study evaluated the prognostic significance of PNI, NLR, and PLR in predicting overall survival in newly diagnosed multiple myeloma patients.

  • 2

    Low PNI (≤34.7) was found in 39.2% of patients and was associated with significantly higher mortality compared to the high PNI group.

  • 3

    Median overall survival was significantly shorter in the low PNI group at 13.5 months compared to 53.3 months in the high PNI group.

  • 4

    No significant differences in median overall survival were observed between low and high PLR or NLR groups in this study.

  • 5

    High beta-2 microglobulin levels were associated with a 3.19-fold increased risk of death among the patients studied.

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