High end-of-life incidence of seizures and status epilepticus in patients with primary and secondary brain tumors

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Seizures are a common symptom in patients with primary brain tumors and brain metastases, often leading to initial diagnosis.
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The risk of developing epilepsy in patients with primary brain tumors ranges from 20% to 80%, higher than in those with brain metastases.
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Non-convulsive status epilepticus (NCSE) is challenging to diagnose, with a previous study showing 2% of brain tumor patients presenting with it.
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The incidence of clinically observed seizures at the end of life in neuro-oncological patients may exceed previously reported rates of 6% to 56%.
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The study included 68 patients, with 58.8% diagnosed with primary brain tumors and 41.2% with brain metastases or related conditions.

Journal Of Neuro-Oncology

by Sophie von Brauchitsch, Adam Strzelczyk, Felix Rosenow, Elisabeth Neuhaus, Daniel Dubinski, Joachim P. Steinbach, Martin Voss
November 3, 2022

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