Patient Characteristics and Clinical Outcomes of Acute Pyelonephritis Treated in Mayo Clinic's Hospital-at-Home Program - Takeaways - MDSpire

Patient Characteristics and Clinical Outcomes of Acute Pyelonephritis Treated in Mayo Clinic's Hospital-at-Home Program

  • By

  • Cesar A Gomez-Cabello

  • Igor Dumic

  • Michael J Maniaci

  • Margaret R Paulson

  • Aryan Shiari

  • Leah W Webster

  • Jeni McGrew

  • Ariana Genovese

  • Bernardo Collaco

  • Maissa Trabilsy

  • Antonio J Forte

  • Wendelyn Bosch

  • January 15, 2026

  • 0 min

Share

  • 1

    The study evaluated outcomes of 165 patients with acute pyelonephritis managed in Mayo Clinic's Advanced Care at Home program from July 2020 to January 2025.

  • 2

    Patients had a median age of 67 years, with 30.9% meeting sepsis criteria and 47.3% presenting with acute kidney injury upon admission.

  • 3

    The median length of stay in the home-based care program was 3.1 days, with only 4.8% requiring escalation to a traditional hospital.

  • 4

    Readmission rates were 17.0%, and 4.8% of patients had emergency department visits within 30 days post-discharge, with no in-program deaths.

  • 5

    The study demonstrates that acute pyelonephritis can be safely managed in a hospital-at-home setting with appropriate patient selection and infrastructure.

Original Source(s)

Patient Characteristics and Clinical Outcomes of Acute Pyelonephritis Treated in Mayo Clinic's Hospital-at-Home Program

  • by Cesar A Gomez-Cabello, Igor Dumic, Michael J Maniaci, Margaret R Paulson, Aryan Shiari, Leah W Webster, Jeni McGrew, Ariana Genovese, Bernardo Collaco, Maissa Trabilsy, Antonio J Forte, Wendelyn Bosch

  • January 15, 2026

Related Content

Comparative efficacy and safety of immunomodulatory therapies for sepsis: a systematic review and network meta-analysis

Macrophage metabolic reprogramming in sepsis-associated acute lung injury: mechanisms and therapeutic strategies

The prognostic value of the CALLY index in sepsis: a systematic review and meta-analysis