Comparison of Photon-Counting CT and V/Q SPECT for Assessing Lobar Perfusion in Chronic Thromboembolic Pulmonary Hypertension - Takeaways - MDSpire

Comparison of Photon-Counting CT and V/Q SPECT for Assessing Lobar Perfusion in Chronic Thromboembolic Pulmonary Hypertension

  • By

  • Matthias M. V. Moeskes

  • Thorsten Derlin

  • Anna M. Hunkemöller

  • Cornelia Schäfer-Prokop

  • Norman Kornemann

  • Jan W. Eckstein

  • Bernhard Meyer

  • Jens Vogel-Claussen

  • Frank K. Wacker

  • Hoen-oh Shin

  • April 24, 2026

  • 0 min

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  • 1

    Chronic thromboembolic pulmonary hypertension (CTEPH) often goes underrecognized, leading to advanced disease stages at diagnosis.

  • 2

    V/Q-SPECT is the first-line imaging modality for CTEPH but has limitations in detecting centrally located thromboembolic lesions.

  • 3

    Photon-counting computed tomography (PCCT) offers superior image quality and detailed perfusion assessment compared to V/Q-SPECT.

  • 4

    The study evaluated the agreement between PCCT-derived perfusion maps and V/Q-SPECT in patients with suspected or confirmed CTEPH.

  • 5

    PCCT may reduce the need for additional perfusion imaging by providing reliable lobar perfusion metrics essential for treatment planning.

Original Source(s)

Comparison of Photon-Counting CT and V/Q SPECT for Assessing Lobar Perfusion in Chronic Thromboembolic Pulmonary Hypertension

  • by Matthias M. V. Moeskes, Thorsten Derlin, Anna M. Hunkemöller, Cornelia Schäfer-Prokop, Norman Kornemann, Jan W. Eckstein, Bernhard Meyer, Jens Vogel-Claussen, Frank K. Wacker, Hoen-oh Shin

  • April 24, 2026

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