Potential Role of IL-6 and IL-17 as Biomarkers in Early-Onset Coronary Artery Disease: A Cross-Sectional Analysis - Takeaways - MDSpire

Potential Role of IL-6 and IL-17 as Biomarkers in Early-Onset Coronary Artery Disease: A Cross-Sectional Analysis

  • By

  • Kexin Yang

  • Sheng Liu

  • Chenyang Wang

  • Siyao Ni

  • Zhijian Yue

  • Ludan Bi

  • Yunxiao Yang

  • Ming Zhang

  • January 20, 2026

  • 0 min

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  • 1

    Coronary artery disease (CAD) is the leading cause of death globally, with early-onset cases increasing among younger populations.

  • 2

    Premature coronary artery disease (pCAD) is defined as CAD occurring before age 55 in men and 65 in women, significantly impacting quality of life.

  • 3

    Cytokines like IL-6 and IL-17 are linked to CAD progression and may serve as biomarkers for early detection and personalized treatment strategies.

  • 4

    The study analyzed 986 patients, focusing on the association of cytokine levels with pCAD and conventional cardiovascular risk factors.

  • 5

    Findings aim to provide insights into gender-specific variations in cytokine levels and their diagnostic value for early-onset CAD.

Original Source(s)

Potential Role of IL-6 and IL-17 as Biomarkers in Early-Onset Coronary Artery Disease: A Cross-Sectional Analysis

  • by Kexin Yang, Sheng Liu, Chenyang Wang, Siyao Ni, Zhijian Yue, Ludan Bi, Yunxiao Yang, Ming Zhang

  • January 20, 2026

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