Standardized Lacrimal Sac Massage vs Probing for Congenital Nasolacrimal Duct Obstruction in Infants: A - Takeaways - MDSpire
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Comparative Effectiveness of Standardized Lacrimal Sac Massage and Probing in Treating Congenital Nasolacrimal Duct Obstruction in Infants

  • By

  • Xinyu Zheng

  • Xinyue Yu

  • Guangsen Wu

  • Jiayi Zhang

  • Kerui Wang

  • Ling Jin

  • Siyu Huang

  • Rongxin Chen

  • Huiying Yu

  • Weifeng Huang

  • Zuohong Li

  • Xuanwei Liang

  • September 1, 2026

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  • 1

    Congenital nasolacrimal duct obstruction (CNLDO) affects 5% to 20% of infants, with spontaneous resolution decreasing from 95% to 32% as age increases.

  • 2

    Lacrimal probing is effective but invasive, carrying risks such as trauma and infection, while lacrimal sac massage is noninvasive and cost-effective.

  • 3

    This randomized clinical trial aimed to compare the efficacy of lacrimal sac massage and lacrimal duct probing in treating CNLDO in infants.

  • 4

    Participants underwent block randomization and received standardized training for lacrimal sac massage, while probing was performed under topical anesthesia.

  • 5

    The primary efficacy endpoint was the resolution rate at 3 months, defined as substantial improvement of epiphora without purulent discharge.

Original Source(s)

Standardized Lacrimal Sac Massage vs Probing for Congenital Nasolacrimal Duct Obstruction in Infants: A

  • by Xinyu Zheng, Xinyue Yu, Guangsen Wu, Jiayi Zhang, Kerui Wang, Ling Jin, Siyu Huang, Rongxin Chen, Huiying Yu, Weifeng Huang, Zuohong Li, Xuanwei Liang

  • September 1, 2026

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