The role of postmastectomy radiotherapy in male breast cancer: a multicenter retrospective study - Takeaways - MDSpire

The role of postmastectomy radiotherapy in male breast cancer: a multicenter retrospective study

  • By

  • Xi Wang

  • Yingli Lin

  • Zongjie Zheng

  • YongTian Chen

  • May 8, 2026

  • 0 min

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  • 1

    Male breast cancer (MBC) accounts for about 1% of all breast cancers, with treatment largely based on female breast cancer studies.

  • 2

    Postmastectomy radiotherapy (PMRT) was associated with improved overall survival (OS) in MBC patients, particularly those with high-risk features.

  • 3

    In a cohort of 714 SEER patients, 33.9% received PMRT, showing better OS for T2 tumors and patients with multiple positive lymph nodes.

  • 4

    Competing risk analysis indicated no significant difference in breast cancer-specific survival (BCSS) between PMRT and non-PMRT groups.

  • 5

    The findings support PMRT use in high-risk MBC patients and emphasize the need for personalized treatment strategies.

Original Source(s)

The role of postmastectomy radiotherapy in male breast cancer: a multicenter retrospective study

  • by Xi Wang, Yingli Lin, Zongjie Zheng, YongTian Chen

  • May 8, 2026

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