Folic acid deficiency as a modifiable risk factor for anastomotic leak in patients undergoing colorectal cancer surgery - Takeaways - MDSpire

Folic acid deficiency as a modifiable risk factor for anastomotic leak in patients undergoing colorectal cancer surgery

  • By

  • Andrea Chirivella-Fernandez

  • Javier Rivera-Castellano

  • Ester Ramírez-Caballero

  • Samuel Morales-Díaz

  • Luciano Delgado-Plasencia

  • June 4, 2025

  • 0 min

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  • 1

    Folic acid deficiency is linked to radiological sarcopenia and may increase the risk of anastomotic leak in colorectal cancer surgery patients.

  • 2

    Computed tomography effectively assesses muscle density, aiding in the preoperative identification of sarcopenia in colorectal cancer patients.

  • 3

    The study included 250 patients, with 16% diagnosed with radiological sarcopenia and 12% exhibiting insufficient preoperative folic acid levels.

  • 4

    Patients with radiological sarcopenia had a significantly lower mean psoas density compared to those without sarcopenia.

  • 5

    Statistical analysis revealed a strong association between low folic acid levels and the presence of radiological sarcopenia.

Original Source(s)

Folic acid deficiency as a modifiable risk factor for anastomotic leak in patients undergoing colorectal cancer surgery

  • by Andrea Chirivella-Fernandez, Javier Rivera-Castellano, Ester Ramírez-Caballero, Samuel Morales-Díaz, Luciano Delgado-Plasencia

  • June 4, 2025

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