Ten-year follow-up of degenerative spinal lesions on radiographs and MRI in axial spondyloarthritis: results of the DESIR (DEvenir des spondylarthropathies indifférenciées récentes) cohort - Takeaways - MDSpire

Ten-year follow-up of degenerative spinal lesions on radiographs and MRI in axial spondyloarthritis: results of the DESIR (DEvenir des spondylarthropathies indifférenciées récentes) cohort

  • By

  • Laura Pina Vegas

  • Miranda van Lunteren

  • Damien Loeuille

  • Caroline Morizot

  • Esther Newsum

  • Sofia Ramiro

  • Floris van Gaalen

  • Alain Saraux

  • Pascal Claudepierre

  • Antoine Feydy

  • Désirée van der Heijde

  • Monique Reijnierse

  • March 6, 2025

  • 0 min

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  • 1

    Axial spondyloarthritis (axSpA) is a chronic inflammatory disease primarily affecting the spine and can lead to degenerative spinal lesions (DLs).

  • 2

    In the DESIR cohort, nearly 30% of axSpA patients had spinal DLs on radiographs and over 70% on MRI at baseline.

  • 3

    The long-term evolution of DLs in axSpA patients is under-researched, with uncertainty about the progression of these lesions over time.

  • 4

    The presence of DLs can delay the diagnosis of axSpA by approximately three years, impacting treatment decisions.

  • 5

    The study aims to report the occurrence of DLs over 10 years in axSpA patients and identify factors associated with their progression.

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