Image-guided puncture for differentiating malignant from benign peritoneal lesions: a systematic review and meta-analysis

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Image-guided puncture is a minimally invasive method for differentiating benign from malignant peritoneal lesions.
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Diagnostic sensitivity of image-guided puncture ranges from 64% to 98%, while specificity ranges from 86% to 100%.
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Traditional biopsy methods carry risks such as infection and tumor dissemination, making image-guided techniques preferable.
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The systematic review included 15 eligible studies, assessed for quality using the QUADAS-2 tool.
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Meta-analysis utilized random-effects models to account for heterogeneity, providing conservative estimates of diagnostic performance.

European Radiology

by Yi-Lin Hou, Jia-Yue Sun, Xue-Mei Wang, Zhi-Guang Chen, Xi-Yu Zhang, Cheng-Fei Sun, Di Wu, Yun-Fei Zhang
November 20, 2025

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