Timing and microbiological profile influence long-term outcomes after debridement, antibiotics, and implant retention (DAIR) in acute hip periprosthetic joint infection - Takeaways - MDSpire

Timing and microbiological profile influence long-term outcomes after debridement, antibiotics, and implant retention (DAIR) in acute hip periprosthetic joint infection

  • By

  • Ernesto Muñoz-Mahamud

  • Juan Carlos Perdomo-Lizarraga

  • Andrés Combalia

  • Alfonso Alías

  • Adrià Serra

  • Jenaro Ángel Fernández-Valencia

  • Miguel Ángel Verdejo

  • Álex Soriano

  • June 23, 2026

  • 0 min

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  • 1

    Periprosthetic joint infection (PJI) accounts for 13%-17% of hip revision procedures and is a serious complication post-hip arthroplasty.

  • 2

    The debridement, antibiotics, and implant retention (DAIR) strategy aims to eradicate acute PJI while preserving well-fixed prosthetic components.

  • 3

    This study evaluated treatment failure-free survival at five years in 115 patients treated with DAIR for acute PJI following hip arthroplasty.

  • 4

    Infections were classified as early acute or delayed acute based on the timing of onset, with a mean follow-up of 7.1 years for the cohort.

  • 5

    Treatment failure was defined by events such as revision surgery, additional debridement, long-term antibiotic therapy, or PJI-related mortality.

Original Source(s)

Timing and microbiological profile influence long-term outcomes after debridement, antibiotics, and implant retention (DAIR) in acute hip periprosthetic joint infection

  • by Ernesto Muñoz-Mahamud, Juan Carlos Perdomo-Lizarraga, Andrés Combalia, Alfonso Alías, Adrià Serra, Jenaro Ángel Fernández-Valencia, Miguel Ángel Verdejo, Álex Soriano

  • June 23, 2026

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