Prognostic value of systemic inflammation response index in successfully recanalized acute large vessel occlusion stroke patients: a retrospective study - Takeaways - MDSpire

Prognostic value of systemic inflammation response index in successfully recanalized acute large vessel occlusion stroke patients: a retrospective study

  • By

  • Wangyu Zhang

  • Congcong Zhou

  • Xuan Xu

  • Guomei Du

  • Shuqin Liang

  • Tong Xu

  • Han Zhao

  • Jiaou Chen

  • May 28, 2026

  • 0 min

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  • 1

    This study evaluated the prognostic significance of the Systemic Inflammation Response Index (SIRI) in acute large vessel occlusion stroke patients post-recanalization.

  • 2

    A total of 287 successfully recanalized ALVOS patients were enrolled, with a mean age of 70.9 years and 58.5% being male.

  • 3

    Higher baseline SIRI levels were significantly associated with poor functional outcomes at 90 days, with mean SIRI levels differing between outcome groups.

  • 4

    The area under the ROC curve for SIRI predicting poor outcomes was 0.63, and its incorporation improved prognostic accuracy in an age + NIHSS model.

  • 5

    No significant association was found between SIRI levels and hemorrhagic transformation or symptomatic intracranial hemorrhage in the study cohort.

Original Source(s)

Prognostic value of systemic inflammation response index in successfully recanalized acute large vessel occlusion stroke patients: a retrospective study

  • by Wangyu Zhang, Congcong Zhou, Xuan Xu, Guomei Du, Shuqin Liang, Tong Xu, Han Zhao, Jiaou Chen

  • May 28, 2026

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